Neuroimaging & Neurocircuitry Core

CORE LEADERSHIP AND ADMINISTRATION

Directors: Timothy Roberts, Ph.D. (robertstim@email.chop.edu) and Douglas Coulter, Ph.D. (coulterd@email.chop.edu)
Co-Director: Eric Marsh, M.D., Ph.D. (marshe@email.chop.edu)
Co-Investigator (7T small animal MRI): Hao Huang, Ph.D.
Bioengineer: Hajime Takano, Ph.D.
Neurophysiologist: Cuiyong Yue, Ph.D.
Research Technician (EEG): Almedia McCoy
Research Assistant (Imaging): Matthew Ku

The Neuroimaging and Neurocircuitry Core (NNC) enables the study of changes in brain circuitry which occur in people with IDD. The Core supports research in both patients and animal models by providing users the following state-of-the-art technologies.

CORE SERVICES

  • Magnetoencephalographic (MEG) recordings of brain activity (Director: Roberts)
  • Magnetic resonance imaging (MRI) studies of brain structure and function (Director: Roberts)
  • Multiphoton, confocal, and epifluorescence microscopic imaging studies of the dynamics of neuronal circuit function (Director: Coulter)
  • Patch clamp recording studies in neurons (Director: Coulter)
  • Electroencephalographic (EEG) and other in vivo recordings. Analyses are performed in affected human patients with IDD, in Preclinical animal models of IDD, and in vitro (stem cells and tissue culture). (Director: Marsh)