Intellectual and Developmental
Disabilities Research Center

IDDRC Seminar Series

The Center sponsors a monthly seminar series during the academic year. Seminars are held at The Children’s Hospital of Philadelphia, Abramson Research Center, Conference Room 123-ABC from Noon to 1:00 p.m.

All interested individuals, including those without current NIH or NSF funding, are encouraged to attend the monthly seminars that the Center sponsors during the academic year. Seminars are held at The Children’s Hospital of Philadelphia, Abramson Research Center, Conference Room 123-ABC from Noon to 1:00 p.m. Lunch is provided. Questions about the seminar series can be directed to Kristen Pidgeon at

Please click here to download the 2019-2020 IDDRC Seminar Series schedule.

September 10, 2010
Dr. Terrie Inder, Associate Professor in Pediatrics, Neurology and Radiology
Washington University in St. Louis, St. Louis, MO
The Pathway to Improving Neurological Outcomes in High Risk Infants—Where Are We At?

September 28, 2010
Dr. Vince Calhoun, Associate Professor Department of Electrical and Computer Engineering Neurosciences and Computer Science***
University of New Mexico, Albuquerque, NM
ICA-Analysis and Simulation of Multimodal Brain Imaging and Genetic Datasets
***Co-sponsored with Center for Autism Research

October 12, 2010
Dr. Satoshi Minoshima, Professor of Radiology and Bioengineering
University of Washington, Seattle, WA
Imaging Investigations of Aging

November 9, 2010
Dr. Kimberly Huber, Associate Professor, Department of Neuroscience
University of Texas Southwestern Medical Center, Dallas, TX
Control of Synapse Development and Plasticity by Fragile X Mental Retardation Protein

December 14, 2010
Dr. Mark Mattson, Chief, Cellular and Molecular Neurosciences Section
National Institutes on Aging/National Institute of Health, Bethesda, MD
Signaling Pathways that Help Neurons Help Themselves

January 11, 2011
Dr. BJ Casey, Director of Sackler Institute for Developmental Psychology
A Neurodevelopmental Approach to Mental Health and Illness: From Human Imaging to Mouse Genetics

February 8, 2011
Dr. Dr. Joseph Piven, Sarah Graham Kenen Professor of Psychiatry, Pediatrics and Psychology
The University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC
Updates on Studies of Autism

March 8, 2011
Dr. Pat Levitt, Provost Professor of Neuroscience, Pediatrics, Psychiatry and Pharmacy
Keck School of Medicine of University of South California, Los Angeles, CA
Seretonin, Fetal-Maternal Interactions, and Brain Development

April 12, 2011
Dr. Mustafa Sahin, Assistant Professor in Neurology
Children's Hospital of Boston, Boston, MA
Axonal Connectivity in Tuberous Sclerosis as a Model for Neurodevelopmental Disorders

May 6, 2011
Dr. Bruce McEwen, Alfred E. Mirsky Professor***
The Rockefeller University, New York, NY
Sex, Stress and the Brain: Hormone Actions Above the Hypothalamus Via Novel Mechanisms
***Co-Sponsored by School of Veterinary Medicine Neuroscience Center, School of Medicine Department of Genetics, Institute on Aging, Women's Behavioral Wellness Center & Mahoney INS

June 14, 2011
Dr. Eric Rappaport, Scientific Director, NAPCore Facility
The Children's Hospital of Philadelphia Research Institute

September 13, 2011
Dr. Michael Sutton, Assistant Professor, Department of Molecular & Integrative Physiology
University of Michigan/The Molecular & Behavioral Neuroscience Institute, Ann Arbor, MI
Tuning Neurotransmission through Local Protein Synthesis at the Synapse

October 11, 2011
Dr. Dean Wong, Professor of Radiology, Neurosciences, Psychiatry and Environmental Health Sciences
The Johns Hopkins University, Baltimore, MD
Molecular Imaging of Neuroreceptor Systems in Neuropsychiatry and CNS Drug Development

November 8, 2011
Dr. Jeffrey Golden, Pathologist-in-Chief and Professor of Pathology and Laboratory Medicine
The Children's Hospital of Philadelphia, Philadelphia, PA
An Expaaaaanding Role for ARX in Normal and Abnormal Brain Development

December 13, 2011
Dr. Hakon Hakonarson, Associate Professor of Pediatrics
The Children's Hospital of Philadelphia, Philadelphia, PA
The Future of Genomic Medicine in Patient Care

January 10, 2012
Dr. Takao Hensch, Professor, Molecular & Cellular Biology/Professor, Neurology (Children's Hospital)
Harvard University/Center for Brain Science, Cambridge, MA
Shaping Neural Circuits by Early Experience

February 14, 2012
Dr. Mei Zhen, Assistant Professor, Department of Medical Genetics and Physiology
University of Toronto, Toronto, Canada
The Development and Operation of the C. Elegans Motor Circuit

March 13, 2012
Dr. Beth Stevens, Assistant Professor of Neurology
Harvard Medical School, Program in Neuroscience, Boston, MA
Pruning CNS Synapses: An Active Role for Glia and the Complement Cascade

April 5, 2012
Dr. David Rowitch, Professor of Pediatrics and Neurological Surgery
University of California, San Francisco, San Francisco, CA
Understanding Glial Development and Roles in Neurological Diseases

April 10, 2012
Dr. Eric Klann, Professor of Neural Science
New York University/The Center for Neural Science, New York, NY
Dysregulated Translational Control in Intellectual and Developmental Disabilities


December 11, 2012
Dr. Gregory L. Holmes, Professor of Medicine (Neurology) and Pediatrics
Dartmouth Medical School – Lebanon, New Hampshire
The Epileptic Encephalopathies: Mechanisms and Treatment

January 8, 2013
Dr. Rosalind Segal, Professor of Neurobiology
Dana-Farber Cancer Institute – Boston, Massachusetts
There and Back Again: Target Derived Neurotrophins Prevent Axonal Degeneration

February 12, 2013
Dr. Christopher Rongo, Professor of Genetics
Rutgers University/The Waksman Institute – Piscataway, New Jersey
Regulated AMPA Receptor Trafficking in C. elegans in Response to Experience and Hypoxic Stress

March 12, 2013
Dr. Elena Pasquale
Neuro-Glia Communication Through Ephrin-A3 and EphA4
Professor of Biology
Sanford-Burnham Medical Research Institute – La Jolla, California

April 9, 2013
Dr. In-Hyun Park, Assistant Professor of Genetics
Yale Stem Cell Center – New Haven, Connecticut
Reprogramming and IT Application: Neurodevelopmental

April 19, 2013
Dr. Maarten van den Buuse, Associate Professor of Pharmacology
University of Melbourne/Florey Institute of Neuroscience and Mental Health – Melbourne, Australia
Neurodevelopmental Animal Models of Schizophrenia: Mental Illness Risk Factors During Adolescent Development

June 11, 2013
Dr. Tracy L. Bale, Associate Professor of Neuroscience
University of Pennsylvania – Philadelphia, Pennsylvania
Stressed-Out Parents and Transgenerational Epigenetics: Sperm and Placental Mechanisms Involved in Reprogramming the Brain

September 10, 2013
Dr. Frances E. Jensen, Professor and Chair of Neurology
University of Pennsylvania/Perelman School of Medicine – Philadelphia, Pennsylvania
Exploring the Shared Neurobiology of Early Life Epilepsy and Autism

November 5, 2013
Dr. Tracy L. Bale, Professor of Neuroscience
University of Pennsylvania/School of Veterinary Medicine – Philadelphia, Pennsylvania
Stressed-Out Parents and Transgenerational Epigenetics: Sperm and Placental Mechanisms Involved in Reprogramming the Brain

December 3, 2013
Dr. Joseph Gleeson, Professor of Neurosciences
University of California, San Diego – La Jolla, California
Exome Sequencing to Advance Diagnosis and Care in Neurodevelopmental Disorders

January 14, 2014
Dr. Thomas L. Schwarz, Professor of Neurology and Neurobiology
Boston Children's Hospital/Harvard Medical School – Boston. Massachusetts
Regulating Mitochondrial Movement: Why it Matters to Neurons

February 11, 2014
Dr. Beth Stevens, Assistant Professor of Neurology
Boston Children's Hospital/Harvard Medical School – Boston, Massachusetts
Immune Mechanisms of Synapse Loss in Development and Disease

March 4, 2014
Dr. Benjamin Philpot, Associate Professor of Cell Biology and Physiology
University of North Carolina/School of Medicine – Chapel Hill, North Carolina
Pharmacogenetic Insights Into Angelman Syndrome

April 15, 2014
Dr. Barry Kosofsky, Chief of Pediatric Neurology and Goldsmith Professor of Pediatrics, Neurology, Neuroscience and Radiology
New York-Presbyterian Hospital/Weill Cornell Medical College
Mechanisms Underlying Prenatal Cocaine Induced Changes in Brain Structure and Function in Mice and Humans

May 13, 2014
Dr. Elliott H. Sherr, Professor of Neurology, Pediatrics
University of California, San Francisco/Institute of Human Genetics – San Francisco, California
Genes, Brain and Behavior, New Tools Help Address Old Problems

September 9, 2014
Dr. Cristina M. Alberini, Professor of Neural Science/Adjunct Professor of Neuroscience
New York University/Icahn School of Medicine at Mount Sinai – New York, New York
Molecular Mechanisms of Memory Consolidation and Enhancement

October 14, 2014
Dr. Benjamin Deneen, Associate Professor of Neuroscience
Baylor College of Medicine – Houston, Texas
Developmental Gliogenesis: The Crossroads of Cell Fate and Malignancy in the CNS
November 11, 2014
Dr. Beverly Davidson, Arthur V. Meigs Chair in Pediatrics/Professor of Pathology & Laboratory Medicine
Children's Hospital of Philadelphia/University of Pennsylvania Perelman School of Medicine – Philadelphia, Pennsylvania
Emerging Therapies for Inherited Brain Diseases

December 9, 2014
Dr. Gordon Fishell, Professor of Neuroscience and Physiology
New York University School of Medicine – New York, New York
Making Up Your Mind: The Integration of Interneurons into Brain Circuitry

January 13, 2015
Dr. Steven Walkley, Professor of Neuroscience, Pathology and Neurology
Albert Einstein College of Medicine/Yeshiva University – Bronx, New York
Lysosomal Disease After a Half Century: A New Era Emerges

February 10, 2015
Dr. Timothy Roberts, Vice Chair of Research for Radiology/Professor of Radiology
Children's Hospital of Philadelphia/University of Pennsylvania Perelman School of Medicine – Philadelphia, Pennsylvania
Electrophysiological Signatures in Autism Spectrum Disorders: Towards Biomarkers

March 10, 2015
Dr. Lori Isom, Interim Chair, Professor of Pharmacology and Molecular & Integrative Physiology       
University of Michigan Medical School – Ann Arbor, Michigan
Roles of Voltage-gated Sodium Channel SCN1A and SCN1B in Epileptic Encephalopathy

April 14, 2015
Dr. Douglas Coulter, Professor of Pediatrics
Children's Hospital of Philadelphia/University of Pennsylvania Perelman School of Medicine – Philadelphia, Pennsylvania
"Neuronal Circuit Mechanisms of Epilepsy: Implications for Therapy"

May 12, 2015
Dr. Evan Eichler, Professor of Genome Sciences
University of Washington/Howard Hughes Medical School – Seattle, Washington
Autism: New Mutations, Genes and Subtypes
**Co-sponsored with the Penn Department of Genetics

September 8, 2015
Christopher Cowen, PhD,
Associate Professor of Psychiatry
Harvard Medical School/McLean Hospital
"Transcriptional Regulation of Cortical Synaptic Transmission and Behaviors Relevant to Autism"

October 13, 2015
Ricardo Dolmetsch, PhD,
Global Head of Neuroscience
Novartis Institutes for Biomedical Research
"A New Day for Drug Discovery"

November 10, 2015
Kathleen Millen, PhD,
Professor of Pediatrics
University of Washington School of Medicine
"Epilepsy caused by megalencephaly & focal cortical dysplasia is acutely treatable with PIK3 inhibition"

December 8, 2015
Michael Fox, PhD,
Associate Professor of Pediatrics
Virginia Tech Carilion Research Institute
"Novel Mechanisms Regulating the Assembly of Circuits & Synapses in the Developing Brain"

January 12, 2016
Joseph Buxbaum, PhD,
G. Harold and Leila Y. Mathers Professor
Mount Sinai School of Medicine
"From Genes to Novel Therapeutics in Autism Spectrum Disorder"

March 8, 2016
Daniel Licht, MD,
Associate Professor of Neurology
Perelman School of Medicine at UPenn/CHOP
"Light and Critical Care– You Can't Know What You Don't Measure"

April 12, 2016
Zhaolan (Joe) Zhou, PhD,
Associate Professor of Genetics
Perelman School of Medicine at UPenn
"Genetic Dissection of Autism Spectrum Disorders in Mice"

September 13, 2016
Craig Powell, MD, PhD,
Associate Professor of Neurology & Neurotherapeutics
UT Southwestern Medical Center
"Genetic Models of Autism: Molecules to Potential Therapeutics"

October 11, 2016
Randy Blakely, PhD,
Professor of Biomedical Sciences
Florida Atlantic University
"In Vivo Modeling of Dopamine Transporter Leak Syndrome—A Search for Deeper Insights into the Mechanisms Underlying ADHD"

November 8, 2016
Nicole Calakos, MD, PhD,
Associate Professor of Neurology & Neurobiology
Duke University Medical Center
"From Healthy Habits to Pathological Compulsions: New Views on Circuit Mechanisms"

December 13, 2016
Jennifer Darnell, PhD,
Research Associate Professor
The Rockefeller University
"Translational Control by the Fragile X Mental Retardation Protein, FMRP: Targets and Mechanism"

February 14, 2017
Amelia Eisch, PhD,
Children’s Hospital of Philadelphia/Perelman School of Medicine at UPenn
"New Hippocampal Neurons in the Postnatal Brain: Familiar Circuits, Novel Perspectives"

April 11, 2017
Michela Fagiolini, PhD,
Assistant Professor of Neurology
Harvard University
"Circuits Dissection and New Therapies in Rett Syndrome"

May 9, 2017
David Lynch, MD, PhD,
Professor of Neurology
Children’s Hospital of Philadelphia/Perelman School of Medicine at UPenn
"Friedreich Ataxia: Neurodegenerative Disease or Developmental Disorder"

October 10, 2017
Elliott Sherr, MD, PhD,
Professor of Neurology
University of California San Francisco
"The Brain's Superhighway: A Shovel Ready Infrastructure Project"

December 12, 2017
Helen Tager-Flusberg, PhD,
Professor of Psychological & Brain Sciences
Boston University
"Early Markers for Language Impairment in Autism"

January 9, 2018
Matthew Anderson, MD, PhD,
Associate Professor of Neuroscience
Harvard Medical School
"A Cellular and Molecular Locus for Sociability Deficits in Autism"

February 13, 2018
Raquel Gur, MD, PhD,
The Karl & Linda Rickels Professor of Psychiatry
Perelman School of Medicine at University of Pennsylvania
"The Confluence of Cognitive Deficits and Psychopathology in Relation to Neurodevelopment"

March 13, 2018
Stephan Sanders, PhD,
Assistant Professor of Psychiatry
University of California, San Francisco
"Phenomics - Collecting Genetic and Phenotype Data at Scale in Autism Spectrum Disorder"

April 10, 2018
Martha Farah, PhD,
Walter H. Annenberg Professor in Natural Sciences
Perelman School of Medicine at University of Pennsylvania
"Socio-economic Status and Brain Development: From Science to Policy"

May 8, 2018
Bradley Schlaggar, MD, PhD,
A. Ernest & Jane G. Stein Professor of Developmental Neurology
Washington University School of Medicine, St. Louis
"Tourette Syndrome: Insights from Developmental Cognitive Neuroscience"

June 22, 2018
Dani Dumitriu, MD, PhD,
Assistant Professor of Neuroscience
Icahn School of Medicine at Mount Sinai
"Connectomic principles of resilience in a mouse model of social defeat"

September 18, 2018
Jeffrey Neul, MD, PhD,
Professor of Pediatrics
Vanderbilt University
“Rett syndrome: From Natural History to Therapy"

October 9, 2018
Jason Lerch, PhD,
Associate Professor of Medical Biophysics
The Hospital for Sick Children (SickKids)
“Co-Clinical Trials in Autism"

November 13, 2018
Carrie Bearden, PhD,
Professor of Clinical Psychology
University of California Los Angeles
“Convergent Pathways to Psychosis in Clinical and Genetic High-Risk Populations"

December 11, 2018
Sally Temple, PhD,
Scientific Director
Neural Stem Cell Institute
“Human stem cell Modeling of Age-related Neurodegenerative disease"

January 8, 2019
Chris Dulla, PhD,
Assistant Professor of Neuroscience
Tufts University, Sackler School of Graduate Biomedical Sciences
“GABAergic interneurons are looking for some excitement during development"

March 12, 2019
Eric Morrow, MD, PhD,
Associate Professor of Biology
Brown University
“Genetic and cellular mechanisms in human postnatal brain development"

April 9, 2019
Kristen Brennand, PhD,
Associate Professor
Ichan School of Medicine at Mount Sinai
“Modelling the impact of common and rare variants to schizophrenia using stem cells"

May 14, 2019
David Kleinfeld, PhD,
Professor of Physics
University of California San Diego
"Sensory and internal signals for brainstem control of active sensing"