The New Program Development Award program was previously supported as part of the IDDRC at CHOP/Penn with funding from the Eunice Kennedy Shriver National Institutes of Child Health and Human Development (NICHD) when the Center was supported as a P30 mechanism.
With the most recent competitive renewal, the mechanism switched to a U54 and New Program Development was excluded from eligibility. Thankfully, Dr. Bryan Wolf, Chief Scientific Officer and Executive Vice President at CHOP and Dr. Jonathan Epstein, Chief Scientific Officer and Executive Vice Dean at Penn, have agreed to provide funding so that the program can be reinstated. This program is also supported from funding received from The Philadelphia Foundation.
The Center anticipates making three to four awards of up to $50,000 per year for two years. The second year of support is contingent upon demonstration of adequate progress. For more information about this award, please contact Kristen Pidgeon at email@example.com
David Lynch, MD, PhD
Project Title: "Developmental Expression of the NMDA Receptor"
Jeffrey Golden, MD
Project Title: "Sonic Hedgehog and Brain Development"
Timothy Crombleholme, MD
Project Title: "Intrauterine Gene Therapy"
Paul Wang, MD
Project Title: "Cognitive Patterns in Williams Syndrome"
Haruhiko Siomi, PhD
Project Title: "Fragile X Syndrome—Etiology"
Jeffrey Ming, MD
Project Title: "BMP Receptor and Brain Development"
Edwin (Ted) Abel, PhD
Project Title: "Albright's Osteodystrophy"
Douglas Epstein, PhD
Project Title: "Dopaminergic Systems and ADHD"
Peter Crino, MD, PhD
Project Title: "Candidate Genes for Autism and Mental Retardation in TSC"
Kenro Kusumi, PhD
Project Title: "Developmental Genetic Analysis of the Mouse DII3 Neuroventricular Mutant Model for Human Fetal Hydrocephalus"
Tony Simon, PhD
Project Title: "Parietal Lobe Function in Children with 22q11.2 Deletion"
Edward (Ted) Brodkin, MD
Project Title: "Developing a Mouse Model of an Autism Endophenotype: Genetic Analysis of Social Approach-Avoidance Behavior in Inbred Mouse Strains"
Carsten Bönnemann, MD
Project Title: "Extracellular Ligands of the Sarcoglycan Complex as Candidates for Muscular Dystrophy with and without Mental Retardation"
Edward Cooper, MD, PhD
Project Title: "Regulation and Diversity of Brain KCNQ Channels"
Matthew Dalva, PhD
Project Title: "EphB- and NMDAR-dependent assembly of synaptic proteins"
Zissimos Mourelatos, MD
Project Title: "Molecular Dissection of the Fragile X Mental Retardation Protein – microRNA Connection"
Brenda Porter, MD, PhD
Project Title: "Environmental Influences on Dentate Granule Neuron Maturation"
Eric Marsh, MD, PhD
Project Title: "Arx Gene Mutations and Cortical Development and Mental Retardation"
Matthew Deardorff, MD, PhD
Project Title: "The Cohesin Complex and Mental Retardation"
Marni Falk, MD
Project Title: "Impact of PPAR Pathway Modulating Agents on Primary Mitochondrial Dysfunction in C. Elegans"
Sangwon Kim, PhD
Project Title: "Thyroid Hormone Inducible Small GTPase, Rhes-mediated Iron Trafficking and Neuronal Function"
Zhaolan (Joe) Zhou, PhD
Project Title: "Modeling Rett Syndrome with Transgenic Mice"
Bassil Kublaoui, MD, PhD, FAAP
Project Title: "Could Neonates with Prader-Willi Syndrome be Dying from Failure to Thrive Due to the Absence of One Neuropeptide-Oxytocin?"
Neil Sondheimer, MD, PhD
Project Title: "Stem-Cell Based Approaches to the Reduction of Disease-Associated Mitochondrial Heteroplasmy"
Benjamin Yerys, PhD
Project Title: "Quantitative Proteomic Profiling of mGluR Signaling Pathways in Fragile X Syndrome: Biomarker Discovery"
Marc Fuccillo, MD, PhD
Project Title: "Exploring Striatal Circuit Genetic Interactions Driving Autism Pathophysiology"
Matthew Kayser, MD, PhD
Project Title: "Molecular and neural mechanisms of social behavioral dysregulation in NF1"
Yuanquan Song, PhD
Project Title: "Investigate the ATR-Chk1 pathway in regulating axon regeneration in Drosophila and Mice"
Ethan Goldberg, MD, PhD
Project Title: "Novel precision therapy in an experimental model of a progressive myoclonus ataxia"